Cai Lab News

Long Cai receives NIH Director's Pioneer Award

Oct 6, 2022

NIH has announced Long Cai is a recipient of its prestigious Pioneer Award. This award from the High-Risk, High Reward Research Program supports individual s...

Cai Lab BBQ 2022

Apr 26, 2022

Spring is in full swing on the Caltech campus and Cai Lab is celebrating! Leaving our bench work behind, the whole team had a much needed break beneath the t...

News feature: Revealing chromosome contours, one dot at a time

Feb 21, 2022

Nature interviews Cai Lab in this week's Technology Feature. In a vivid review article, Long Cai, along with Mitch Guttman (Caltech) and peers, describe how ...

Our paper "Single-cell nuclear architecture across cell types in the mouse brain" published in Science

Nov 1, 2021

Our latest work is now available in print inside the latest issue of Science. Using integrated spatial genomics technology, researchers at Cai Lab extensivel...

Presentation video: Integrated spatial genomics reveals invariant features in the nucleus

Oct 15, 2021

Looking to delve into how integrated spatial genomics is revealing new insights in nuclear protein arrangement and function? You can watch a complete recordi...

New publication " Integration of spatial and single-cell transcriptomic data elucidates mouse organogenesis"

Sep 10, 2021

Exciting new work "Integration of spatial and single-cell transcriptomic data elucidates mouse organogenesis" is now out in Nature Biotechnology! This public...

Congrats to Dr. Takei and Dr. Eng on their defense!

Jun 11, 2021

Cai Lab is thrilled to celebrate the hard work and accomplishments of our two lab members graduating today. Dr. Yodai Takei, who's recent work uses imaging-b...

Preprint: "Integrated spatial genomics in tissues reveals invariant and cell type dependent nuclear architecture"

Apr 29, 2021

Our latest work "Integrated spatial genomics in tissues reveals invariant and cell type dependent nuclear architecture" is available to view as a preprint. W...

Cai Lab has a new home!

Feb 24, 2021

We're thrilled to make the move to the brand new Chen Neuroscience Research Building. We're already feeling at home in this beautiful, modern lab space. The ...

"Nuclear Physics": Imaging into the Heart of a Cell

Feb 2, 2021

Delve into the big ideas of Cai Lab's latest research in this interview with authors Yodai Takei and Long Cai. Read the article at caltech.edu "The advantage...

New paper in Nature "Integrated spatial genomics reveals global architecture of single nuclei""

Jan 28, 2021

Take a look at the latest work from Cai Lab now in Nature. The work describes a new "single-cell multimodal imaging approach where genome organization, nucle...

Preprint: Global architecture of the nucleus in single cells by DNA seqFISH+ and multiplexed immunofluorescence

Dec 1, 2020

Check out our latest preprint with seqFISH-based integrated spatial genomics approach to study chromosome organization, transcriptional states, and chromatin...

Elsy Buitrago-Delgado: 100 Inspiring Hispanic/Latinx Scientists in America

Sep 17, 2020

Congratulations to Elsy Buitrago-Delgado for being named one of Cell's 100 Inspiring Hispanic/Latinx Scientists in America! Her research studying spatial org...

New Publication: Detecting Proteins In Situ with DUET

Aug 3, 2020

Exciting new work by Cai Lab and lead author Yandong Zhang demonstrates a strategy for measuring proteins and their post-translational modification (PTM) sta...

Elsy Buitrago-Delgado: Awarded 2019 HHMI Hanna H. Gray Fellowship

Sep 12, 2019

Congratulations to Elsy for being one of fifteen scientists awarded the 2019 HHMI Hanna H. Gray Fellowship! Click here to learn more!

Congratulations to the new Dr. Yandong Zhang!

May 29, 2019

Congratulations Dr. Yandong Zhang for a successful PhD defense! His thesis work titled “Highly Multiplexed Imaging of E. Coli Chromosome and Sensitive Detect...

Lab Retreat 2019: Ojai, California

May 23, 2019

This May, the Cai Lab headed out to beautiful Ojai for a weekend of hiking, delicious food, and discussing our science! A fantastic time for all, can't wait ...

New Super-Resolution Technique Published in Nature

Mar 28, 2019

Work at Cai lab published by first author Chee Huat (Linus) Eng in the March 25, 2019 issue of Nature. Also featured in Caltech News this week, the paper des...